June 27, 2013
Researchers at Stanford University of Medicine (SUM) have revealed that while 15 to 45 percent of men in the US are deemed infertile, there is a bigger risk to consider – cancer.
Their study has concluded that there is a viable connection between testicular cancer and male infertility.
Michael Eisnberg, assistant professor of urology at SUM explained that the evidence they produced shows that infertility may be the “barometer for men’s overall health.”
Looking at previous research conducted on 2,238 men from the Baylor College of Medicine (BCM) and the Texas Cancer Registry (TCR), Eisenberg’s team estimated that infertility began at an average of 35 years of age with testing on sperm counts.
Only 29 of the 2,238 men who participated in the studies were diagnosed with testicular cancer; however the researchers maintain that there is a correlation between azoospermic infertility that would allude to a 3 times likelihood that men would develop cancer within the overall population.
It must be pointed out that undiagnosed males who developed cancer were not entered into the statistical data which led researchers to postulate that the problem may be bigger than they assume.
Eisenberg stated that by the age of 30, men were at risk for testicular cancer because of:
• Blockage preventing sperm to be released
• Sperm not being produced in large enough quantities prior to ejaculation.
Eisenberg said : “The thought was that if the testicles don’t develop correctly, and they can’t produce sperm…the normal pathways get dysregulated, which perhaps leads to cancer.”
SUM confirmed that obstructions within the testies were part of the problem. This could be relieved with surgery; however there are assumed limited options for azoospermia sufferers.
According to the study: “Men with azoospermia have an increased risk of subsequently developing cancer, suggesting a possible common etiology between azoospermia and cancer development. Additional follow-up of azoospermic men after reproductive efforts end may be warranted.”
While SUM are trying to uncover causation of male infertility, researchers have successfully developed a “birth-control pill” for men. Calling the drug JQ1, this chemical cocktail stunts sperm production in mice. According to a newly published study , researchers are calling this discovery an “efficacious strategy for a male contraceptive.”
By blocking the proteins essential for sperm production and drastically lowering sperm counts, JQ1 is now being slated for human trials.
JQ1 is a molecule that is so small it can travel through blood barriers and impede the male body’s ability to produce sperm. While trials in mice showed that they became infertile, their sexual drive was not affected.
Dr. Martin Matzuk , professor of molecular biology, molecular and human genetics, and pharmacology at the BCM, maintains that: “If you stop the drug, there’s complete reversibility.”
The BCM has a long history of working to expanding the eugenics agenda with the use of genetic technologies; including collaboration with the German Nazis and their march toward using genetics to create a “better human race”.
By looking for “justice as fairness” with the ethical practice of genetics and eugenics concerning applied science and social constructs. The advantage of eugenics ideology in genetic technology is viewed as “the greatest benefit of individuals with the least advantages.”
And so by subverting the fact of eugenics in genetic advances will alleviate prejudice and make sure that the eugenics agenda is devoid of negative perceptions so that the genetically disadvantaged could be touted as the beneficiaries of eugenic applications in genetic technologies.
Dr. James E. Bradner, a researcher at the Dana-Farber Cancer Institute and Harvard Medical School, says that JQ1 can also be used to treat cancer. JQ1 binds to genes connected with proteins that necessitate fertility. Bradner says: “This compound produces a rapid and reversible decrease in sperm count and motility with profound effects on fertility.”
Matzuk discovered the molecule Bradner needed to continue with experiments into causing male infertility.
According to the study, “Our findings demonstrate that, when given to rodents, this compound produces a rapid and reversible decrease in sperm count and mobility with profound effect on fertility.”